Chance’s rehabilitation veterinarian recommended we begin supplementing with MYOS Canine Muscle Formula at our last visit to help try to combat Chance’s muscle atrophy, or muscle loss, so I decided to do some research.
I ordered the “over-the-counter” (OTC) strength formula from an online pet supply company listed on the MYOS company website after we got home from the rehab vet. The rehab vet said they’d seen excellent results and she was trying to order the veterinary-strength formula but it was out-of-stock at the manufacturer level. The veterinary-strength formula contains additional branched-chain amino acids that the OTC-strength product does not. These additional amino acids provide a little extra muscle support. I figured we’d try the OTC-strength formula to see how Chance did on it while waiting on the veterinary-strength formula to come in. 
MYOS Canine Muscle Formula contains Fortetropin® which comes from fertilized chicken egg yolks. Clinical studies have shown that Fortetropin® helps build lean muscle and also helps decrease muscle loss after orthopedic surgeries.    
What is Fortetropin®? It is a “proteolipid complex” that is also a myostatin reducer which sounds pretty impressive. A proteolipid is a protein that is made up of high amounts of lipids, or fats, and is found in tissues throughout the body. A proteolipid complex is just a bunch of these proteolipids, or fatty proteins, that have joined together to make a single bigger proteolipid. A myostatin is a protein found mainly in skeletal muscle that stops muscle growth so muscles don’t grow too big. Myostatins circulate in the blood stream so they move throughout the body instead of staying in one place.    
The rehab vet feels Chance’s muscle atrophy, or muscle loss, is age-related. This means Chance’s body isn’t producing as much of the proteolipid complexes that help build and maintain muscle as it used to which is allowing her to lose muscle in certain areas even with good nutrition and healthy exercise. By supplementing with something that not only helps build and maintain muscle but also reduces the myostatins responsible for stopping muscle growth, we hope to help her body start to rebuild this lost muscle.
Chance so far has loved her MYOS Canine Muscle Formula so we will be switching to the veterinary product as soon as we can. She will have been on MYOS Canine Muscle Formula for exactly 3 weeks at her next rehab vet appointment. We are hoping we have good muscle news to report after that visit.
 About Fortetropin
Myos Rens Technology
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 Fortetropin Inhibits Disuse Muscle Atrophy In Dogs After Tibial Plateau Leveling Osteotomy
White DA, Harkin KR, Roush JK, Renberg WC, Biller D (2020)
Fortetropin Inhibits Disuse Muscle Atrophy In Dogs After Tibial Plateau Leveling Osteotomy.
PLoS ONE 15(4): e0231306.
© 2020 White et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 The Effects of Fortetropin Supplementation on Body Composition, Strength, and Power in Humans and Mechanism of Action in a Rodent Model
Sharp MH, Lowery RP, Mobley CB, Fox CD, de Souza EO, Shields KA, Healy JC, Arick NQ, Thompson RM, Roberts MD, Wilson JM.
The Effects of Fortetropin Supplementation on Body Composition, Strength, and Power in Humans and Mechanism of Action in a Rodent Model.
J Am Coll Nutr. 2016 Nov-Dec;35(8):679-691. doi: 10.1080/07315724.2016.1142403. Epub 2016 Jun 22. PMID: 27333407.
 Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled Study
William Evans, PhD, Mahalakshmi Shankaran, PhD, Edna Nyangau, BS, Tyler Field, BS, Hussein Mohammed, BS, Robert Wolfe, PhD, Scott Schutzler, RN, Marc Hellerstein, MD, PhD, Effects of Fortetropin on the Rate of Muscle Protein Synthesis in Older Men and Women: A Randomized, Double-Blinded, Placebo-Controlled Study, The Journals of Gerontology: Series A, , glaa162, https://doi.org/10.1093/gerona/glaa162
 MSTN gene: myostatin
Source: MedlinePlus, National Library of Medicine.
 Chapter 8 - Inflammatory and Oxidative Stress Markers in Skeletal Muscle of Obese Subjects
Obesity Oxidative Stress and Dietary Antioxidants, 2018, Pages 163-189
Victoria Catalán, Gema Frühbeck, Javier Gómez-Ambrosi
 Protein Complexes And Functional Modules In Molecular Networks
Victor Spirin, Leonid A. Mirny
Proceedings of the National Academy of Sciences Oct 2003, 100 (21) 12123-12128; DOI: 10.1073/pnas.2032324100
 For Veterinarians
Myos Rens Technology
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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. The information contained in these blogs is not meant as a substitute for veterinary care or as a replacement for advice or instructions given by a veterinarian. Contact your veterinarian before starting any over-the-counter products.
* Vitamin E
* Essential Oils
* DGP - Marine Collagen
* Vitamin C
* Fish Oil